Osteo-D 2000IU Chewable Tablet | Incepta Pharmaceuticals Ltd.
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Home Medicines Osteoporosis Osteo-D 2000IU Chewable Tablet

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Osteo-D 2000IU Chewable Tablet

Generic: Cholecalciferol (Vit. D3).

Type: Tablet

Pack Size: 10 Pcs

Cholecalciferol (Vit. D3)

  • Primary Uses:
    • Osteoporosis
    • Hypoparathyroidism
    • Rickets
    • Osteomalacia
    • Vitamin D deficiency
    • Pseudohypoparathyroidism
    • Familial hypophosphatemia

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✅ Description:

Functions of Vitamin D3

Bone and Teeth Health:

  • Facilitates calcium and phosphate absorption for strong bones and teeth.
  • Prevents conditions like rickets, osteomalacia, and osteoporosis.

Pregnancy and Breastfeeding:

  • Essential to prevent pre-eclampsia in pregnant women.
  • Supports the growing infant's need for this vital nutrient during breastfeeding.

Immune System Support:

  • Plays a critical role in boosting immunity, and reducing the risk of infections and immune-related disorders.

Deficiency Causes

  • Common in individuals who spend extended time indoors or in areas with minimal sunlight.
  • Lack of foods rich in vitamin D3 (e.g., fish, eggs, fortified foods).
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✔️ Dosage Guidelines

Adults:

Nutritional Deficiency:

  • 200–400 IU/day (5–10 mcg).

Osteoporosis (Prophylaxis and Treatment, >50 years):

  • 800–1000 IU/day (20–25 mcg) with calcium supplements.

Hypoparathyroidism:

  • 50,000–200,000 IU/day (0.625–5 mg) with calcium supplements.

Children:

Nutritional Supplementation (RDA):

  • 0–12 months: 400 IU/day (10 mcg).
  • 1–18 years: 600 IU/day (15 mcg).

Vitamin D-Resistant Rickets:

  • 12,000–500,000 IU/day (0.3–12.5 mg).

Familial Hypophosphatemia:

  • 40,000–80,000 IU/day (1–2 mg) with phosphate supplements.
✔️ Administration
  • Oral or IM: This may be taken with or without food.
✔️ Mechanism of Action
  • Vitamin D3 helps regulate calcium and phosphate homeostasis for proper bone mineralization.
  • Essential for calcium absorption in the gastrointestinal tract.
  • Stimulates bone formation and promotes healthy bone structure.
✔️ Side Effects
  • Hypercalcemia syndrome or calcium intoxication, symptoms may include:
    • Anorexia
    • Headache
    • Dry mouth
    • Nausea and vomiting
    • Abdominal pain or constipation
✔️ Drug Interactions
  1. Increased Risk of Hypercalcemia:
    • With thiazide diuretics, calcium, or phosphate supplements.
  2. Reduced Efficacy:
    • With antiepileptics (carbamazepine, phenobarbitone, phenytoin), rifampicin, and isoniazid.
  3. Counteraction:
    • By corticosteroids.
  4. Other Considerations:
    • Reduced absorption when taken with cholestyramine, colestipol, mineral oil, or orlistat.
    • Interaction with digoxin or cardiac glycosides.
    • Ketoconazole may interfere.
✔️ Contraindications
  • Diseases associated with hypercalcemia.
  • Known hypersensitivity to cholecalciferol or any excipients.
  • Evidence of vitamin D toxicity.
✔️ Precautions
  • Caution advised in:
    • High calcium or phosphate levels.
    • Heart problems or kidney disease.
  • Must be paired with adequate calcium and magnesium intake.
  • Use with caution during lactation, as it is distributed in breast milk.
✔️ Key Benefits of Vitamin D3 Supplementation
  • Enhances bone mineral density and reduces fracture risks.
  • Supports muscle function and reduces fall risks in older adults.
  • Aids fetal development and infant growth by ensuring optimal calcium levels.
  • Contributes to a robust immune defense against infections and chronic diseases.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

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